Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782477 | 0.87 | CYP4F2 (0.49) | MAPTKDM4EALDH1A1GAAALOX15 | |
| SCHEMBL7717114 | 0.86 | KDM4E (0.51) | MAPTKDM4EALDH1A1GAAALOX15 | |
| SCHEMBL5778832 | 0.80 | KDM4E (0.60) | MAPTKDM4EALDH1A1GAAALOX15 | |
| SCHEMBL31285975 | 0.80 | KDM4E (0.60) | MAPTKDM4EALDH1A1GAAALOX15 | |
| SCHEMBL14815944 | 0.80 | HRH3 (0.49) | MAPTKDM4EALDH1A1GAAALOX15 | |
| SCHEMBL4682191 | 0.78 | MAPT (0.62) | MAPTKDM4EALDH1A1GAAALOX15 | |
| SCHEMBL30853462 | 0.78 | MAPT (0.62) | MAPTKDM4EALDH1A1GAAALOX15 | |
| SCHEMBL6274911 | 0.78 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1GAAALOX15 | |
| SCHEMBL16595913 | 0.77 | GAA (0.48) | MAPTKDM4EALDH1A1GAAALOX15 | |
| SCHEMBL31478141 | 0.77 | LMNA (0.46) | MAPTALDH1A1LMNACYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402862-B1 | 8-Carboxy-1,2,3,4-tetrahydroquinolin-6-yl-acetic acid and process for its preparation | KYORIN SEIYAKU KK (JP) | 1997-09-10 | — | — | EP | disclosed |
| US-5120743-A | Aids, metabolic bone diseases | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0402862-A2 | Novel cyclic anthranilic acid acetic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-12-19 | — | — | EP | disclosed |