Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767164 | 0.94 | NFE2L2 (0.44) | HRH3NFE2L2HPGDRARARARB | |
| SCHEMBL8767748 | 0.83 | NFE2L2 (0.44) | HRH3NFE2L2HPGDRARARARB | |
| SCHEMBL8767578 | 0.80 | HTR1A (0.42) | HRH3NFE2L2HPGDTDP1HTR1A | |
| SCHEMBL16582474 | 0.79 | NFE2L2 (0.53) | HRH3NFE2L2HPGDHTR1AHTR1D | |
| SCHEMBL8768332 | 0.79 | TDP1 (0.40) | HRH3NFE2L2HPGDTDP1HTR1A | |
| SCHEMBL8767117 | 0.79 | TDP1 (0.40) | HRH3NFE2L2HPGDTDP1HTR1A | |
| SCHEMBL8767790 | 0.79 | TDP1 (0.40) | HRH3NFE2L2HPGDTDP1HTR1A | |
| SCHEMBL30674634 | 0.79 | HRH3 (0.60) | HRH3NFE2L2HPGDPTGES | |
| SCHEMBL8767034 | 0.78 | CYP17A1 (0.42) | RARARARBTDP1 | |
| SCHEMBL17655004 | 0.78 | HRH3 (0.40) | HRH3NFE2L2HPGDRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |