SCHEMBL8768496

SCHEMBL8768496

NCC(=O)NCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8187940 0.78
SCHEMBL3074874 0.78 CA2 (0.44)
SCHEMBL14934 0.77
SCHEMBL9188241 0.77
SCHEMBL992990 0.77
SCHEMBL29952010 0.77
SCHEMBL460909 0.77
SCHEMBL19434714 0.77 GLRA1 (0.47)
SCHEMBL3305420 0.76 ALDH1A1 (0.41)
SCHEMBL25185305 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792146-A1 INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES HEMASURE, INC. (US) 1997-09-03 EP claimed
WO-1997002028-A1 INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES HEMASURE, INC. (US) 1997-01-23 WO claimed
WO-2024020536-A1 HEXACYCLIC TOPOISOMERASE INHIBITORS HAVING CYTOTOXIC ACTIVITY ON CANCER CELLS NJ BIO, INC. (US) 2024-01-25 WO disclosed
WO-2023178641-A1 DNA TOXIC DIMER COMPOUND AND CONJUGATE THEREOF 成都百利多特生物药业有限责任公司 2023-09-28 WO disclosed
WO-2015115091-A1 ANTI-HER2 ANTIBODY-DRUG CONJUGATE 第一三共株式会社 2015-08-06 WO disclosed
WO-2014057687-A1 ANTIBODY-DRUG CONJUGATE 第一三共株式会社 (JP) 2014-04-17 WO disclosed
EP-0792146-A1 INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES HEMASURE, INC. (US) 1997-09-03 EP disclosed
WO-1997002028-A1 INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES HEMASURE, INC. (US) 1997-01-23 WO disclosed