Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3585680 | 0.71 | CSNK2A2 (0.46) | PTGS2CSNK2A2CSNK2A1LMNAADORA2B | |
| SCHEMBL19396826 | 0.69 | PTGS2 (0.47) | PTGS2POLB | |
| SCHEMBL17675513 | 0.68 | PTGS2 (0.46) | PTGS2POLB | |
| SCHEMBL13031346 | 0.66 | CSNK2A2 (0.41) | PTGS2CSNK2A2CSNK2A1LMNAADORA2B | |
| SCHEMBL8768263 | 0.65 | CYP1A2 (0.59) | CSNK2A2CSNK2A1LMNAADORA2BALDH1A1 | |
| SCHEMBL17675317 | 0.65 | GRIN2B (0.43) | PTGS2POLB | |
| SCHEMBL3579547 | 0.65 | CSNK2A2 (0.42) | PTGS2CSNK2A2CSNK2A1LMNAADORA2B | |
| SCHEMBL30193179 | 0.62 | PLAA (0.60) | LMNAALDH1A1POLBMAPT | |
| SCHEMBL4560485 | 0.62 | CSNK2A2 (0.55) | PTGS2CSNK2A2CSNK2A1LMNAADORA2B | |
| SCHEMBL7848634 | 0.62 | PLAA (0.60) | LMNAALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |