SCHEMBL8768669

SCHEMBL8768669

CCCOC(=NNOC(=O)OCC)NC

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
SOAT1 P35610 1/20 0.35
MAPT P10636 1/20 0.34
EPHX1 P07099 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8768226 0.85 ALDH1A1 (0.41) ALDH1A1SOAT1MAPTMGAMGAA
SCHEMBL8393558 0.79 ALDH1A1 (0.39) ALDH1A1SOAT1MAPTMGAMGAA
SCHEMBL8768676 0.78 ALDH1A1 (0.43) ALDH1A1MAPTGAA
SCHEMBL8849797 0.77 RAB9A (0.38) ALDH1A1MAPTEPHX1MGAMGAA
SCHEMBL8391154 0.69 ALDH1A1 (0.43) ALDH1A1SOAT1MAPTMGAMGAA
SCHEMBL7057738 0.68 ALDH1A1 (0.72) ALDH1A1SOAT1MAPTMGAMGAA
SCHEMBL137153 0.68
SCHEMBL28326345 0.67 ALDH1A1 (0.55) ALDH1A1SOAT1MAPTMGAMGAA
Fluoride SCHEMBL29068335 0.66 ALDH1A1 (0.68) ALDH1A1SOAT1MAPTMGAMGAA
SCHEMBL11019424 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0703225-B1 Process for the preparation of alkoxytriazolinones BAYER AG (DE) 1997-09-03 EP disclosed
EP-0703224-B1 Process for the preparation of alkoxytriazolinones BAYER AG (DE) 1997-09-03 EP disclosed
EP-0703225-A1 Process for the preparation of alkoxytriazolinones BAYER AG (DE) 1996-03-27 EP disclosed
EP-0703224-A1 Process for the preparation of alkoxytriazolinones BAYER AG (DE) 1996-03-27 EP disclosed