Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 7/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769129 | 0.84 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDMEN1THRB | |
| SCHEMBL8877436 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDMEN1THRB | |
| SCHEMBL8768669 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAPTGAA | |
| SCHEMBL1598801 | 0.75 | LMNA (0.56) | ALDH1A1MAPTHPGDMEN1THRB | |
| Formaldehyde SCHEMBL28260770 | 0.73 | LMNA (0.53) | ALDH1A1MAPTHPGDMEN1THRB | |
| SCHEMBL449722 | 0.70 | LMNA (0.50) | ALDH1A1MAPTHPGDMEN1THRB | |
| SCHEMBL28003882 | 0.68 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDMEN1THRB | |
| SCHEMBL17473107 | 0.67 | ALOX5 (0.51) | ALDH1A1MAPTHPGDMEN1THRB | |
| SCHEMBL15842895 | 0.67 | LMNA (0.50) | ALDH1A1MAPTHPGDMEN1THRB | |
| SCHEMBL16732166 | 0.67 | LMNA (0.46) | ALDH1A1MAPTHPGDMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703224-B1 | Process for the preparation of alkoxytriazolinones | BAYER AG (DE) | 1997-09-03 | — | — | EP | disclosed |
| EP-0703224-A1 | Process for the preparation of alkoxytriazolinones | BAYER AG (DE) | 1996-03-27 | — | — | EP | disclosed |