SCHEMBL9399671

SCHEMBL9399671

COC(=O)CN(C)c1cccc(-c2ccccc2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.46
GSTO1 P78417 1/20 0.46
ADORA3 P0DMS8 1/20 0.42
USP30 Q70CQ3 1/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.40
ALDH1A1 P00352 2/20 0.40
CNR2 P34972 1/20 0.40
LTB4R Q15722 1/20 0.40
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MITF O75030 1/20 0.40
S1PR4 O95977 1/20 0.40
LMNA P02545 1/20 0.40
S1PR1 P21453 1/20 0.40
STAT3 P40763 1/20 0.40
STAT1 P42224 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9158138 0.88 CNR1 (0.54) CNR1RAB9AMEN1KMT2AMAPT
SCHEMBL25272926 0.80 HSD17B10 (0.36) CNR1GSTO1RAB9AMAPTALDH1A1
SCHEMBL9032570 0.80 GSTO1 (0.45) GSTO1RAB9AMAPTALDH1A1LTB4R
SCHEMBL9032969 0.78 CYP1A2 (0.46) GSTO1MEN1KMT2AMAPTALDH1A1
SCHEMBL8768674 0.78 CLK1 (0.40) RAB9AALDH1A1HPGDSMN1; SMN2NPC1
SCHEMBL25224130 0.76 ALDH1A1 (0.46) ADORA3RAB9AMEN1KMT2AALDH1A1
SCHEMBL9550200 0.75 CNR1 (0.54) CNR1RAB9AMAPTCNR2SMN1; SMN2
SCHEMBL8768691 0.75 ACACB (0.35) CNR1GSTO1RAB9AKMT2AALDH1A1
SCHEMBL12410427 0.75 MKNK1 (0.43)
SCHEMBL28709069 0.73 ALDH1A1 (0.47) GSTO1MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5310919-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1994-05-10 US disclosed
US-5120734-A FUNGICIDAL PYRID-2-YL-AMINO ACETIC ACID ESTERS BAYER AKTIENGESELLSCHAFT (DE) 1992-06-09 US disclosed
US-5008275-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-04-16 US disclosed