Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.54 |
| ▸ | PPARG | P37231 | 10/20 | 0.54 |
| ▸ | PPARD | Q03181 | 5/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925426 | 0.92 | PPARA (0.45) | PPARAPPARGPPARDSOAT1HDAC1 | |
| SCHEMBL8768759 | 0.92 | PPARA (0.53) | PPARAPPARGPPARDSOAT1HDAC1 | |
| SCHEMBL8767784 | 0.89 | PPARA (0.61) | PPARAPPARGPPARDSOAT1HDAC1 | |
| SCHEMBL8767727 | 0.89 | PPARA (0.61) | PPARAPPARGPPARDSOAT1HDAC1 | |
| SCHEMBL8768686 | 0.89 | PPARA (0.61) | PPARAPPARGPPARDSOAT1HDAC1 | |
| SCHEMBL8767679 | 0.89 | PPARA (0.59) | PPARAPPARGPPARDSOAT1HDAC1 | |
| SCHEMBL8924425 | 0.83 | PPARA (0.44) | PPARAPPARGPPARDSOAT1HDAC1 | |
| SCHEMBL8767768 | 0.83 | PPARA (0.56) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8926283 | 0.83 | PPARA (0.68) | PPARAPPARGPPARDPLK1PLK3 | |
| SCHEMBL8924339 | 0.82 | GAA (0.52) | PPARAPPARGPPARDHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |