SCHEMBL5706010

SCHEMBL5706010

CC(C)(C)c1ccc(C(=O)Oc2ccccc2Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.59
MAPT P10636 5/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
TDP1 Q9NUW8 1/20 0.58
RAB9A P51151 3/20 0.54
ALDH1A1 P00352 3/20 0.54
NPC1 O15118 2/20 0.54
GLA P06280 1/20 0.54
ATM Q13315 1/20 0.54
KMT2A Q03164 3/20 0.48
LMNA P02545 2/20 0.48
NR1I2 O75469 1/20 0.48
TP53 P04637 1/20 0.48
AHR P35869 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
TNF P01375 1/20 0.48
KLF5 Q13887 1/20 0.48
NOD1 Q9Y239 1/20 0.48
PRSS1 P07477 1/20 0.46
ACR P10323 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706060 0.88 NPSR1 (0.50) NPSR1MAPTL3MBTL1TDP1RAB9A
SCHEMBL5706048 0.82 SLC6A3 (0.58) MAPTL3MBTL1TDP1RAB9ANPC1
SCHEMBL5706143 0.82 ESR1 (0.56) MAPTL3MBTL1TDP1RAB9AALDH1A1
SCHEMBL5706149 0.82 KMT2A (0.45) NPSR1MAPTL3MBTL1TDP1RAB9A
SCHEMBL3149726 0.82 PTK2B (0.51) NPSR1MAPTRAB9AALDH1A1NPC1
SCHEMBL5706002 0.81 KMT2A (0.63) NPSR1MAPTRAB9ANPC1KMT2A
SCHEMBL13292741 0.81 NPSR1 (0.59) NPSR1MAPTL3MBTL1TDP1RAB9A
SCHEMBL5706248 0.81 HPGD (0.53) NPSR1MAPTRAB9AALDH1A1NPC1
SCHEMBL5705968 0.80 MAPT (0.47) NPSR1MAPTL3MBTL1TDP1RAB9A
SCHEMBL1975083 0.80 HPGD (0.51) NPSR1MAPTRAB9AALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
CN-1131259-C Method for producing polycarbonate resin TEIJIN LTD (JP) 2003-12-17 CN disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
CN-1252817-A Process for producing polycarbonate resin TEIJIN LTD (JP) 2000-05-10 CN disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed