Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768850 | 1.00 | TP53 (0.39) | TP53MMECD274PDCD1LG2ALDH1A1 | |
| SCHEMBL3376844 | 0.84 | ALDH1A1 (0.39) | TP53MMEALDH1A1CA2CA1 | |
| SCHEMBL5074809 | 0.83 | SMN1; SMN2 (0.40) | TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL5074810 | 0.83 | SMN1; SMN2 (0.40) | TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL9603268 | 0.82 | ALDH1A1 (0.37) | TP53MMECD274PDCD1LG2ALDH1A1 | |
| SCHEMBL10207210 | 0.81 | ALDH1A1 (0.39) | TP53MMECD274PDCD1LG2ALDH1A1 | |
| SCHEMBL3677561 | 0.81 | ALDH1A1 (0.39) | TP53MMECD274PDCD1LG2ALDH1A1 | |
| SCHEMBL3677560 | 0.81 | ALDH1A1 (0.39) | TP53MMECD274PDCD1LG2ALDH1A1 | |
| SCHEMBL19355664 | 0.81 | ALDH1A1 (0.39) | TP53MMECD274PDCD1LG2ALDH1A1 | |
| SCHEMBL23961406 | 0.79 | CYP2D6 (0.44) | TP53MMEALDH1A1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | disclosed |