Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294007 | 0.84 | SMN1; SMN2 (0.42) | ALDH1A1MEN1USP2MAPTKMT2A | |
| SCHEMBL3294010 | 0.84 | SMN1; SMN2 (0.42) | ALDH1A1MEN1USP2MAPTKMT2A | |
| SCHEMBL5015591 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1MAPTTP53MMESMN1; SMN2 | |
| SCHEMBL5015593 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1MAPTTP53MMESMN1; SMN2 | |
| SCHEMBL8768847 | 0.82 | TP53 (0.39) | ALDH1A1TP53MMEPDCD1LG2CD274 | |
| SCHEMBL8768850 | 0.82 | TP53 (0.39) | ALDH1A1TP53MMEPDCD1LG2CD274 | |
| SCHEMBL15047670 | 0.81 | CYP1A2 (0.40) | ALDH1A1TP53HSD17B10MMETSHR | |
| SCHEMBL526345 | 0.81 | GABRR1 (0.45) | TP53MMEPDCD1LG2CD274SMN1; SMN2 | |
| SCHEMBL17307362 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1USP2MAPTKMT2A | |
| SCHEMBL2153099 | 0.79 | GABRR1 (0.43) | TP53MMEPDCD1LG2CD274SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236930-A | Aldose reductase inhibitors | MITBUSHI GAS CHEMICAL COMPANY, INC. (JP) | 1993-08-17 | — | — | US | disclosed |