Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074810 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL8768850 | 0.83 | TP53 (0.39) | SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8768847 | 0.83 | TP53 (0.39) | SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL16041452 | 0.83 | ALDH1A1 (0.40) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL16041451 | 0.83 | ALDH1A1 (0.40) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL4622349 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL3294010 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL3294007 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL597202 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL1319707 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | claimed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | claimed |
| EP-1924699-A2 | AUREOBASIDIN A SYNTHETASE | Aureogen Biosciences (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025181-A2 | AUREOBASIDIN A SYNTHETASE | AUREOGEN BIOSCIENCES (US) | 2007-03-01 | — | — | WO | disclosed |
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | disclosed |