Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767887 | 0.91 | PPARA (0.43) | NPC1RAB9APPARAPPARGKMT2A | |
| SCHEMBL8767702 | 0.90 | L3MBTL1 (0.45) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8768885 | 0.90 | PPARA (0.41) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8769019 | 0.89 | UTS2R (0.47) | PPARAPPARGKMT2ATSHRABCB11 | |
| SCHEMBL8768132 | 0.86 | PPARA (0.43) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8767854 | 0.82 | PPARA (0.41) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8768971 | 0.81 | PPARA (0.41) | PPARAPPARGKMT2ATSHRABCB11 | |
| SCHEMBL8767766 | 0.80 | PPARA (0.39) | PPARAPPARGKMT2ATSHRABCB11 | |
| SCHEMBL8768911 | 0.78 | PPARA (0.48) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8768853 | 0.76 | HDAC6 (0.49) | NPC1RAB9APPARAPPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |