Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769019 | 0.85 | UTS2R (0.47) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8768132 | 0.83 | PPARA (0.43) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8767887 | 0.83 | PPARA (0.43) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8768859 | 0.81 | NPC1 (0.42) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8767702 | 0.81 | L3MBTL1 (0.45) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8768885 | 0.81 | PPARA (0.41) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8767854 | 0.79 | PPARA (0.41) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8924986 | 0.78 | PPARA (0.44) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL8768673 | 0.78 | MAPK1 (0.44) | PPARAPPARG | |
| SCHEMBL8767766 | 0.77 | PPARA (0.39) | PPARAPPARGTSHRABCB11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |