Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | FBP1 | P09467 | 3/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769000 | 0.90 | PSEN1 (0.44) | PPARACYP1A2CYP3A4PPARGCNR1 | |
| SCHEMBL8769019 | 0.82 | UTS2R (0.47) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL8767854 | 0.80 | PPARA (0.41) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL8768132 | 0.80 | PPARA (0.43) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL8767887 | 0.80 | PPARA (0.43) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL8767702 | 0.78 | L3MBTL1 (0.45) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL8768859 | 0.78 | NPC1 (0.42) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL8768885 | 0.78 | PPARA (0.41) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL8768971 | 0.77 | PPARA (0.41) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL8767766 | 0.76 | PPARA (0.39) | PPARAABCB11CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |