Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MYOC | Q99972 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685320 | 0.81 | MEN1 (0.48) | MEN1KMT2AGAANPC1MAPT | |
| SCHEMBL3218655 | 0.78 | KMT2A (0.68) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL1088745 | 0.78 | MEN1 (0.46) | MEN1KMT2AGAANPC1MAPT | |
| SCHEMBL1063525 | 0.77 | MEN1 (0.45) | MEN1KMT2AGAANPC1MAPT | |
| SCHEMBL5079966 | 0.74 | KMT2A (0.66) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8649993 | 0.73 | PARL (0.45) | MEN1KMT2AGAANPC1MAPT | |
| SCHEMBL1033030 | 0.73 | MMP9 (0.42) | MEN1KMT2AGAAMAPTNPSR1 | |
| SCHEMBL700858 | 0.73 | KMT2A (0.59) | MEN1KMT2AGAANPC1MAPT | |
| SCHEMBL11763994 | 0.73 | KMT2A (0.59) | MEN1KMT2AGAANPC1MAPT | |
| SCHEMBL1088019 | 0.73 | MMP9 (0.41) | MEN1KMT2AGAANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466833-B1 | PROTEASE INHIBITOR | MERCK PATENT GMBH (DE) | 1997-09-10 | — | — | EP | disclosed |