Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MYOC | Q99972 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1088019 | 0.97 | MMP9 (0.41) | MMP9NLRP3MEN1KMT2ALMNA | |
| SCHEMBL1063525 | 0.93 | MEN1 (0.45) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL1088745 | 0.92 | MEN1 (0.46) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL29629276 | 0.83 | MMP9 (0.47) | MMP9MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL3244930 | 0.82 | ELANE (0.43) | MMP9NLRP3MEN1KMT2ALMNA | |
| SCHEMBL1451494 | 0.79 | MEN1 (0.40) | MMP9NLRP3MEN1KMT2ALMNA | |
| SCHEMBL18507619 | 0.78 | ALDH1A1 (0.39) | MMP9NLRP3MEN1KMT2ALMNA | |
| SCHEMBL8330156 | 0.75 | MEN1 (0.39) | MMP9NLRP3MEN1KMT2ALMNA | |
| SCHEMBL8909746 | 0.74 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1651305 | 0.74 | KMT2A (0.53) | MEN1KMT2ALMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644194-B2 | Cold-adapted protease derived from Pseudoalteromonas arctica PAMC 21717 and uses thereof | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2017-05-09 | — | — | US | disclosed |
| US-9574185-B2 | Cold-adapted protease derived from Pseudoalteromonas arctica PAMC 21717 and uses thereof | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2017-02-21 | — | — | US | disclosed |
| EP-1448995-B9 | ASSAY FOR SCREENING CANDIDATE DRUGS FOR THE TREATMENT OF INFLAMMATORY DISEASES | UNIV ABERDEEN (GB) | 2011-10-12 | — | — | EP | disclosed |
| US-7998474-B2 | Exposing drug to intestinal cells, analysing effect of drug on variation of nuclear export or import or disruption of transcriptional activity of transcription factors from NF-kappa B family, differential histone acetylation of p65 | ROWETT RESEARCH INSTITUTE (GB) | 2011-08-16 | — | — | US | disclosed |
| EP-1448995-B1 | ASSAY FOR SCREENING CANDIDATE DRUGS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ROWETT RES INST (GB) | 2011-01-19 | — | — | EP | disclosed |
| US-20060142171-A1 | Novel alkaline protease | FORSKARPATENT I SYD AB (SE) | 2006-06-29 | — | — | US | disclosed |
| EP-1448995-A1 | ASSAY FOR SCREENING CANDIDATE DRUGS FOR THE TREATMENT OF INFLAMMATORY DISEASES | The Rowett Research Institute (GB) | 2004-08-25 | — | — | EP | disclosed |
| US-20030133875-A1 | Assay for screening candidate drug for the treatment of inflammatory diseases and methods for treating the same | ROWETT RESEARCH INSTITUTE (GB) | 2003-07-17 | — | — | US | disclosed |
| WO-2003046580-A1 | ASSAY FOR SCREENING CANDIDATE DRUGS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ROWETT RESEARCH INSTITUTE (GB) | 2003-06-05 | — | — | WO | disclosed |