Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768132 | 0.88 | PPARA (0.43) | PPARGPPARANLRP3 | |
| SCHEMBL8769019 | 0.85 | UTS2R (0.47) | PPARGPPARA | |
| SCHEMBL8768911 | 0.82 | PPARA (0.48) | PPARGPPARA | |
| SCHEMBL8768713 | 0.80 | PPARA (0.39) | MAPK1PPARGPPARA | |
| SCHEMBL8767887 | 0.79 | PPARA (0.43) | PPARGPPARA | |
| SCHEMBL8767854 | 0.78 | PPARA (0.41) | MAPK1PPARGPPARA | |
| SCHEMBL8768971 | 0.78 | PPARA (0.41) | PPARGPPARA | |
| SCHEMBL8768885 | 0.78 | PPARA (0.41) | PPARGPPARA | |
| SCHEMBL8768859 | 0.78 | NPC1 (0.42) | MAPK1PPARGPPARA | |
| SCHEMBL8767702 | 0.78 | L3MBTL1 (0.45) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0639178-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS. | WELLCOME FOUND (GB) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992010468-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-06-25 | — | — | WO | disclosed |