Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.80 |
| ▸ | PDE4A | P27815 | 1/20 | 0.78 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.78 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.78 |
| ▸ | FLT3 | P36888 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | CTSL | P07711 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31611889 | 1.00 | ABCG2 (0.80) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8769002 | 1.00 | ABCG2 (0.80) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30383668 | 0.90 | ABCG2 (0.80) | ABCG2FLT3MEN1LMNAHPGD | |
| SCHEMBL4969738 | 0.90 | ABCG2 (0.80) | ABCG2FLT3MEN1LMNAHPGD | |
| SCHEMBL13696689 | 0.90 | ABCG2 (0.80) | ABCG2FLT3MEN1LMNAHPGD | |
| SCHEMBL633909 | 0.88 | PDE4A (1.00) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL633910 | 0.88 | PDE4A (1.00) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL633045 | 0.88 | ABCG2 (0.97) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL633046 | 0.88 | ABCG2 (0.97) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL634098 | 0.87 | PDE4A (0.82) | ABCG2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629602-B1 | 3,4-Dihydroxychalcone derivatives | NIPPON HYPOX LAB INC (JP) | 1997-09-10 | — | — | EP | disclosed |
| EP-0629602-A1 | 3,4-Dihydroxychalcone derivatives | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5276058-A | Antiinflammatory agents | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1994-01-04 | — | — | US | disclosed |