SCHEMBL4969738

SCHEMBL4969738

COc1ccc(C(=O)C=Cc2ccc(O)c(O)c2)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 5/20 0.80
MAOB P27338 1/20 0.79
MAPT P10636 3/20 0.78
TNFRSF1A P19438 1/20 0.78
XDH P47989 1/20 0.76
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
NPC1 O15118 1/20 0.70
RAB9A P51151 1/20 0.70
FLT3 P36888 1/20 0.69
LMNA P02545 1/20 0.68
HPGD P15428 1/20 0.68
USP2 O75604 1/20 0.67
MAPK1 P28482 1/20 0.67
TLR9 Q9NR96 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383668 1.00 ABCG2 (0.80) ABCG2MAOBMAPTTNFRSF1AXDH
SCHEMBL13696689 1.00 ABCG2 (0.80) ABCG2MAOBMAPTTNFRSF1AXDH
SCHEMBL19783025 0.92 ABCG2 (0.81) ABCG2MAOBMAPTTNFRSF1AXDH
SCHEMBL25202046 0.92 ABCG2 (0.81) ABCG2MAOBMAPTTNFRSF1AXDH
SCHEMBL25210764 0.92 ABCG2 (0.81) ABCG2MAOBMAPTTNFRSF1AXDH
SCHEMBL25197304 0.92 ABCG2 (0.81) ABCG2MAOBMAPTTNFRSF1AXDH
SCHEMBL30383701 0.92 ABCG2 (0.81) ABCG2MAOBMAPTTNFRSF1AXDH
SCHEMBL8769007 0.90 ABCG2 (0.80) ABCG2MAOBMEN1KMT2AFLT3
SCHEMBL8769002 0.90 ABCG2 (0.80) ABCG2MAOBMEN1KMT2AFLT3
SCHEMBL31611889 0.90 ABCG2 (0.80) ABCG2MAOBMEN1KMT2AFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
EP-1254658-B1 REMEDIES FOR THE TREATMENT OF NERVE DIORDERS TAKARA BIO INC (JP) 2008-09-24 EP disclosed
US-7268160-B2 Remedies TAKARA BIO, INC. (JP) 2007-09-11 US disclosed
US-20030144316-A1 Remedies TAKARA BIO INC. (JP) 2003-07-31 US disclosed
EP-1254658-A1 REMEDIES TAKARA BIO INC. (JP) 2002-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MAOB 1004/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAOB 2435/4885MAPT 3512/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAOB 2435/4885MAPT 3512/4885
US-20030144316-A1 Remedies NGF, BDNF, NTRK2 ABCG2 4875/4885MAOB 1306/4885MAPT 1407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.