Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176180 | 1.00 | MEN1 (0.33) | MEN1KMT2ANPC1RAB9ASTS | |
| SCHEMBL8768102 | 0.94 | STS (0.33) | MEN1KMT2ASTS | |
| SCHEMBL8768790 | 0.92 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL8768966 | 0.91 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL8768158 | 0.89 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL9171847 | 0.84 | NR3C1 (0.39) | — | |
| SCHEMBL13417509 | 0.82 | PGR (0.35) | HSD11B1 | |
| SCHEMBL8653316 | 0.76 | LMNA (0.38) | HSD11B1 | |
| SCHEMBL8768961 | 0.76 | LMNA (0.38) | HSD11B1 | |
| SCHEMBL9172523 | 0.76 | LMNA (0.38) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5426102-A | Antigestagenic, antiandrogenic, antiglucocorticoid, antimineralcorticoid properties | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-20 | — | — | US | disclosed |