Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161939 | 0.76 | TSHR (0.39) | CASP1ALDH1A1SMN1; SMN2GAACHRNB2 | |
| SCHEMBL8868983 | 0.75 | TSHR (0.37) | ALDH1A1SMN1; SMN2TDP1MAPTCYP3A4 | |
| SCHEMBL9547259 | 0.75 | MAPT (0.36) | CASP1ALDH1A1MAPTCACNA1BAPBA1 | |
| SCHEMBL9547177 | 0.75 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4TDP1 | |
| SCHEMBL14313840 | 0.75 | TSHR (0.53) | TSHRHPGD | |
| SCHEMBL9190708 | 0.74 | TSHR (0.36) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6332036 | 0.73 | TSHR (0.56) | TSHRHPGD | |
| SCHEMBL21674360 | 0.73 | L3MBTL1 (0.38) | SMN1; SMN2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2654974 | 0.73 | CASP1 (0.56) | CASP1ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL8865298 | 0.72 | EPHX2 (0.43) | MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579102-B1 | Liquid chromatography stationary phases with reduced silanol interactions | WATERS INVESTMENTS LTD (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5374755-A | Silica substrate with silanol surface groups blocked by (substituted)dialkylcarbamates | MILLIPORE CORPORATION (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0579102-A1 | Liquid chromatography stationary phases with reduced silanol interactions | WATERS INVESTMENTS LIMITED (US) | 1994-01-19 | — | — | EP | disclosed |