Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352999 | 0.83 | CES2 (0.52) | — | |
| SCHEMBL5613025 | 0.82 | CES2 (0.57) | AKR1C3ALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL12238334 | 0.81 | ALDH1A1 (0.52) | AKR1C3ALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL10647658 | 0.81 | BCL2 (0.53) | AKR1C3ALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL9233419 | 0.81 | ALDH1A1 (0.50) | AKR1C3ALDH1A1ATML3MBTL1CYP2C9 | |
| SCHEMBL8609177 | 0.81 | NR4A1 (0.47) | TDP1MEN1KMT2AMAPTHPGD | |
| SCHEMBL5070586 | 0.81 | ALDH1A1 (0.59) | AKR1C3ALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL29287571 | 0.81 | CYP2C8 (0.47) | AKR1C3ALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL10644840 | 0.80 | HPGD (0.48) | AKR1C3ALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL8732922 | 0.80 | LMNA (0.44) | ALDH1A1TDP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168218-A | Preparation of substituted benzopinacols | EASTMAN KODAK COMPANY (US) | 1979-09-18 | — | — | US | claimed |
| CN-109912917-B | Isolation tectorial membrane for soil restoration and preparation method thereof | 杭州益壤环境科技集团有限公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-101805298-A | Novel aryl-with heteroaryl-piperazine | HIGH POINT PHARMACEUTICALS LLC | 2010-08-18 | — | — | CN | disclosed |
| CN-1628109-A | Novel aryl-and heteroaryl-piperazines | NOVO NORDISK AS (DK) | 2005-06-15 | — | — | CN | disclosed |
| EP-0293115-B1 | Melt-stable poly(arylene thiotherketone) and production process thereof | KUREHA CHEMICAL IND CO LTD (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5070100-A | COMPLICATIONS OF DIABETES | ALCON LABORATORIES, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-4895925-A | HEAT RESISTANT MOLDING MATERIAL | KUREHA KAGAKU KOGYO K.K. (JP) | 1990-01-23 | — | — | US | disclosed |
| US-4886871-A | REACTING ALKALI METAL SULFIDE AND DIHALOGENATED COMPOUNDS | KUREHA KAGAKU KOGYO K. K. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0293115-A2 | Melt-stable poly(arylene thiotherketone) and production process thereof | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-11-30 | — | — | EP | disclosed |
| EP-0147299-B1 | PROCESS FOR THE PREPARATION OF BENZOPHENONES | RHONE-POULENC CHIMIE (FR) | 1988-03-02 | — | — | EP | disclosed |
| US-4618726-A | DEACTIVATED BENZENE COMPOUND WITH CARBONYL HALIDE IN LIQUID HYDROFLUORIC ACID AND BORON TRIFLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1986-10-21 | — | — | US | disclosed |
| EP-0147299-A2 | Process for the preparation of benzophenones | RHONE-POULENC CHIMIE (FR) | 1985-07-03 | — | — | EP | disclosed |