Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 12/20 | 0.49 |
| ▸ | AR | P10275 | 11/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769113 | 0.90 | PGR (0.48) | PGRARNR3C1LMNAMAPT | |
| SCHEMBL8769481 | 0.76 | PGR (0.48) | PGRARNR3C1LMNAMAPT | |
| SCHEMBL7882963 | 0.75 | LMNA (0.62) | PGRARNR3C1LMNAMAPT | |
| SCHEMBL9472235 | 0.75 | LMNA (0.62) | PGRARNR3C1LMNAMAPT | |
| SCHEMBL8721585 | 0.75 | PGR (0.54) | PGRARNR3C1LMNAMAPT | |
| SCHEMBL8724556 | 0.75 | PGR (0.54) | PGRARNR3C1LMNAMAPT | |
| SCHEMBL13768844 | 0.75 | PGR (0.76) | PGRARNR3C1LMNAABCB11 | |
| SCHEMBL8769769 | 0.74 | PGR (0.51) | PGRARNR3C1LMNAMAPT | |
| SCHEMBL8769005 | 0.74 | PGR (0.51) | PGRARNR3C1LMNAMAPT | |
| SCHEMBL7887184 | 0.74 | PGR (0.65) | PGRARNR3C1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027209-A1 | NEW SUBSTITUTED 19-NOR-PREGNANE DERIVATIVES | LABORATOIRE THERAMEX (MC) | 1997-07-31 | — | — | WO | disclosed |
| EP-0785211-A1 | New substituted 19-nor-pregnane derivatives | LABORATOIRE THERAMEX (MC) | 1997-07-23 | — | — | EP | disclosed |