Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 14/20 | 0.48 |
| ▸ | AR | P10275 | 13/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769113 | 0.86 | PGR (0.48) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769792 | 0.81 | PGR (0.61) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769771 | 0.80 | PGR (0.59) | PGRARNR3C1CYP3A4ABCB11 | |
| SCHEMBL8769023 | 0.79 | PGR (0.67) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769794 | 0.77 | PGR (0.48) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769755 | 0.77 | PGR (0.36) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL14952624 | 0.76 | PGR (0.80) | PGRARNR3C1ABCB11CHRM2 | |
| SCHEMBL12943048 | 0.76 | PGR (0.80) | PGRARNR3C1ABCB11CHRM2 | |
| SCHEMBL8769455 | 0.76 | PGR (0.49) | PGRARNR3C1CYP3A4ABCB11 | |
| SCHEMBL8769087 | 0.72 | PGR (0.56) | PGRARNR3C1PDE4DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785211-A1 | New substituted 19-nor-pregnane derivatives | LABORATOIRE THERAMEX (MC) | 1997-07-23 | — | — | EP | disclosed |