Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 13/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.72 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16810050 | 0.88 | OPRM1 (0.82) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Morphine SCHEMBL3476851 | 0.87 | OPRD1 (0.82) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Morphine SCHEMBL11045706 | 0.86 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL154049 | 0.86 | OPRD1 (0.82) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL13998949 | 0.86 | OPRD1 (0.82) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL17302927 | 0.86 | OPRD1 (0.82) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL16922133 | 0.86 | OPRD1 (0.82) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL7940016 | 0.86 | OPRD1 (0.82) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL8769523 | 0.86 | OPRD1 (0.75) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL3476300 | 0.85 | OPRM1 (0.72) | OPRD1OPRM1OPRK1MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793664-A1 | MORPHINE AND CODEINE DERIVATIVES FOR USE IN THERAPY | BTG INTERNATIONAL LIMITED (GB) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016063-A1 | MORPHINE AND CODEINE DERIVATIVES FOR USE IN THERAPY | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-05-30 | — | — | WO | disclosed |