Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.61 |
| ▸ | AR | P10275 | 7/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769087 | 0.91 | PGR (0.56) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769144 | 0.88 | PGR (0.51) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769138 | 0.88 | PGR (0.51) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL7887184 | 0.85 | PGR (0.65) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769481 | 0.81 | PGR (0.48) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL25334510 | 0.79 | PGR (0.72) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL10951986 | 0.79 | PGR (0.72) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL22400061 | 0.79 | PGR (0.72) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL29403102 | 0.79 | PGR (0.72) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL10954178 | 0.79 | PGR (0.72) | PGRARNR3C1PDE4DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027209-A1 | NEW SUBSTITUTED 19-NOR-PREGNANE DERIVATIVES | LABORATOIRE THERAMEX (MC) | 1997-07-31 | — | — | WO | disclosed |
| EP-0785211-A1 | New substituted 19-nor-pregnane derivatives | LABORATOIRE THERAMEX (MC) | 1997-07-23 | — | — | EP | disclosed |