Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77736 | 0.81 | LMNA (0.61) | ESR1KDM4ELMNAADORA3KMT2A | |
| SCHEMBL8769410 | 0.79 | THRB (0.53) | KDM4ELMNATP53KMT2ASMN1; SMN2 | |
| SCHEMBL13593977 | 0.79 | LMNA (0.46) | ESR1KDM4ELMNATP53ADORA3 | |
| SCHEMBL6398627 | 0.78 | ESR1 (0.42) | ESR1KDM4ELMNAADORA3KMT2A | |
| SCHEMBL11085028 | 0.75 | LMNA (0.50) | ESR1KDM4ELMNAADORA3KMT2A | |
| SCHEMBL12157332 | 0.71 | ESR2 (0.47) | ESR1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL11097401 | 0.70 | LMNA (0.58) | ESR1KDM4ELMNAADORA3KMT2A | |
| SCHEMBL28470699 | 0.65 | TDP1 (0.67) | KDM4ELMNATP53KMT2AESR2 | |
| SCHEMBL1014744 | 0.65 | TDP1 (0.67) | KDM4ELMNATP53KMT2AESR2 | |
| SCHEMBL29743248 | 0.64 | ESR2 (0.44) | ESR1KDM4EADORA3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647630-B1 | Process for producing 5-arylhydantoins | SHOWA DENKO KK (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5606071-A | Process for preparing 5-arylhydantoins using 5-hydantoin, a halogenating agent and p-phenol | SHOWA DENKO K.K. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0647630-A1 | Process for producing 5-arylhydantoins | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-04-12 | — | — | EP | disclosed |