SCHEMBL8769864

SCHEMBL8769864

C=Cc1ccc(CC)cc1[SiH](C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
ALDH1A1 P00352 3/20 0.31
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.30
USP2 O75604 1/20 0.30
GAA P10253 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10917043 0.84 ALDH1A1 (0.43) CYP1A2NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL3972895 0.78 TRPA1 (0.41) TRPA1CYP1A2CYP2A6NPC1RAB9A
SCHEMBL7131356 0.75 ALDH1A1 (0.35) TRPA1CYP1A2CYP2A6NPC1RAB9A
SCHEMBL1264062 0.75 TRPA1 (0.39) TRPA1CYP1A2CYP2A6NPC1RAB9A
SCHEMBL668126 0.75 TRPA1 (0.39) TRPA1CYP1A2CYP2A6NPC1RAB9A
SCHEMBL11425918 0.75
SCHEMBL29600683 0.75 TRPA1 (0.39) TRPA1CYP1A2CYP2A6NPC1RAB9A
SCHEMBL4870800 0.74 NQO1 (0.42) CYP1A2NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL5670692 0.73 TRPA1 (0.38) TRPA1CYP1A2CYP2A6NPC1RAB9A
SCHEMBL6003693 0.73 TDP1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604401-B1 Production of a catalyst component for producing crystalline polymers CHISSO CORP (JP) 1997-09-24 EP disclosed
EP-0395391-B1 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0564004-B1 A highly stereoregular polypropylene CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0404519-B1 A process for producing a high-stiffness polypropylene CHISSO CORP (JP) 1996-08-07 EP disclosed
EP-0604401-A2 Production of a catalyst component for producing crystalline polymers CHISSO CORPORATION (JP) 1994-06-29 EP disclosed
EP-0564004-A1 A highly stereoregular polypropylene CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5173540-A Coordination catalyst comprising titanium compound, organo aluminum compound electron donor and a polymer support; transparent, voidless films produced CHISSO CORPORATION (JP) 1992-12-22 US disclosed
US-5077341-A Using coordination catalyst CHISSO CORPORATION (JP) 1991-12-31 US disclosed
EP-0395391-A2 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORPORATION (JP) 1990-10-31 EP disclosed