SCHEMBL6003693

SCHEMBL6003693

C=Cc1ccc(Cl)cc1[SiH](C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.34
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
F7 P08709 1/20 0.32
F3 P13726 1/20 0.32
DYRK1A Q13627 1/20 0.32
ERN1 O75460 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11425918 0.78
SCHEMBL7911987 0.73 ALDH1A1 (0.35) ALDH1A1
SCHEMBL28422184 0.73 TDP1 (0.44) TDP1ALDH1A1GABRA1GABRG2GABRB3
SCHEMBL8166439 0.73
SCHEMBL4872017 0.73 CYP1A2 (0.44) TDP1ALDH1A1ERN1TP53
SCHEMBL8769864 0.73 TRPA1 (0.35) ALDH1A1
SCHEMBL31615190 0.72 CYP3A4 (0.41) TDP1ALDH1A1GABRA1GABRG2GABRB3
SCHEMBL589945 0.72 CYP3A4 (0.41) TDP1ALDH1A1GABRA1GABRG2GABRB3
SCHEMBL10917043 0.72 ALDH1A1 (0.43) TDP1ALDH1A1GABRA1TP53
SCHEMBL109034 0.72 TDP1 (0.60) TDP1ALDH1A1GABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060142500-A1 Multi-branched styrene-conjugated diene block copolymer and its preparation method KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2006-06-29 US claimed
US-20050182191-A1 Multi-branched styrene-conjugated diene block copolymer and its preparation method KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2005-08-18 US claimed
US-20040059075-A1 Styrene copolymer KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2004-03-25 US claimed
CN-114478953-A Preparation method of three-arm comb-shaped star-branched butyl rubber 中国石油天然气股份有限公司 2022-05-13 CN disclosed
CN-114478954-A Preparation method of wide-distribution four-arm comb-shaped star-branched butyl rubber 中国石油天然气股份有限公司 2022-05-13 CN disclosed
CN-114478950-A Three-arm comb-shaped star-branched butyl rubber and preparation method thereof, and preparation method of three-arm star-shaped nucleating agent 中国石油天然气股份有限公司 2022-05-13 CN disclosed
CN-114478955-A Preparation method of wide-distribution four-arm comb-shaped star-branched butyl rubber 中国石油天然气股份有限公司 2022-05-13 CN disclosed
CN-114478956-A Preparation method of high-width-distribution three-hybrid-arm comb-shaped star-branched butyl rubber 中国石油天然气股份有限公司 2022-05-13 CN disclosed
CN-114478951-A Preparation method of wide-distribution three-arm comb-shaped star-branched butyl rubber 中国石油天然气股份有限公司 2022-05-13 CN disclosed
CN-114478949-A Preparation method of wide-distribution three-arm comb-shaped star-branched butyl rubber 中国石油天然气股份有限公司 2022-05-13 CN disclosed
CN-114478957-A Preparation method of four-arm comb-shaped star-branched butyl rubber 中国石油天然气股份有限公司 2022-05-13 CN disclosed
CN-114163585-A Preparation method of ultra-wide distribution four-hybrid-arm comb-shaped star-branched butyl rubber 中国石油天然气股份有限公司 2022-03-11 CN disclosed
US-20060293466-A1 Methods for synthesis of graft polymers THE UNIVERSITY OF WATERLOO (CA) 2006-12-28 US disclosed
US-20060142500-A1 Multi-branched styrene-conjugated diene block copolymer and its preparation method KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2006-06-29 US disclosed
US-20050182191-A1 Multi-branched styrene-conjugated diene block copolymer and its preparation method KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2005-08-18 US disclosed
US-6756448-B2 SYNDIOTACTIC; LIVING BUTADIENE OR ISOPRENE POLYMER BY ANIONIC POLYMERIZATION WITH ALKYLLITHIUM CATALYST AND THEN REACTION WITH A P-SILYLSTYRENE TERMINAL MODIFIER; FURTHER COPOLYMERIZATION WITH STYRENE KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2004-06-29 US disclosed
US-20040059075-A1 Styrene copolymer KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2004-03-25 US disclosed