Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669394 | 0.83 | KIF11 (0.60) | KIF11PTPN5CYP2C9TAAR1CYP3A4 | |
| SCHEMBL1421311 | 0.79 | KIF11 (0.56) | KIF11PTPN5CYP2C9TAAR1CYP3A4 | |
| SCHEMBL16439869 | 0.78 | KIF11 (0.65) | KIF11PTPN5CYP2C9TAAR1CYP3A4 | |
| SCHEMBL25808753 | 0.78 | KIF11 (0.65) | KIF11PTPN5CYP2C9TAAR1CYP3A4 | |
| Biphenyl SCHEMBL28313556 | 0.74 | ALDH1A1 (0.60) | KIF11PTPN5TAAR1CYP3A4HSD17B10 | |
| Hydrazine SCHEMBL27541145 | 0.73 | KIF11 (0.90) | KIF11PTPN5BACE1ALDH1A1TSHR | |
| SCHEMBL28070215 | 0.72 | KIF11 (0.56) | KIF11PTPN5CYP2C9TAAR1CYP3A4 | |
| SCHEMBL9579980 | 0.72 | KCNN4 (0.52) | KIF11TAAR1ALDH1A1PTPN1KCNN4 | |
| SCHEMBL163728 | 0.72 | KIF11 (1.00) | KIF11PTPN5BACE1ALDH1A1TSHR | |
| SCHEMBL25013355 | 0.72 | KIF11 (0.47) | KIF11PTPN5CYP2C9TDP1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793671-A1 | PHENYLSUBSTITUTED 4-AZASTEROID FLUORODERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-09-10 | — | — | EP | disclosed |
| WO-1997010257-A1 | PHENYLSUBSTITUTED 4-AZASTEROID FLUORODERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-03-20 | — | — | WO | disclosed |