Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.45 |
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | CTSS | P25774 | 5/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | CTSC | P53634 | 4/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338258 | 0.87 | CTSC (0.45) | CTSLCTSKCTSSCTSBCTSC | |
| SCHEMBL10338259 | 0.87 | CTSC (0.45) | CTSLCTSKCTSSCTSBCTSC | |
| SCHEMBL22885981 | 0.85 | CTSS (0.57) | CTSLCTSKCTSSCTSB | |
| SCHEMBL5651683 | 0.78 | TRPM8 (0.50) | CTSLCTSBTRPM8MMP8ALDH1A1 | |
| SCHEMBL5650046 | 0.78 | TRPM8 (0.50) | CTSLCTSBTRPM8MMP8ALDH1A1 | |
| SCHEMBL6091546 | 0.78 | TRPM8 (0.50) | CTSLCTSBTRPM8MMP8ALDH1A1 | |
| SCHEMBL5652568 | 0.77 | TRPM8 (0.55) | CTSLTRPM8L3MBTL1MMP8ALDH1A1 | |
| SCHEMBL5653520 | 0.77 | TRPM8 (0.55) | CTSLTRPM8L3MBTL1MMP8ALDH1A1 | |
| SCHEMBL6075360 | 0.77 | TRPM8 (0.55) | CTSLTRPM8L3MBTL1MMP8ALDH1A1 | |
| SCHEMBL17275392 | 0.76 | CTSS (0.54) | CTSLCTSKCTSSCTSBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793673-A1 | ALPHA-KETOAMIDE DERIVATIVES AS CATHEPSIN L INHIBITOR | Takeda Chemical Industries, Ltd. (JP) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016079-A2 | ALPHA-KETOAMIDE DERIVATIVES AS CATHEPSIN L INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1996-05-30 | — | — | WO | disclosed |