Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | PYGL | P06737 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091546 | 1.00 | TRPM8 (0.50) | TRPM8MMP8PYGLATMCTRB1 | |
| SCHEMBL5650046 | 1.00 | TRPM8 (0.50) | TRPM8MMP8PYGLATMCTRB1 | |
| SCHEMBL5652568 | 0.90 | TRPM8 (0.55) | TRPM8MMP8PYGLATMCTRB1 | |
| SCHEMBL6075360 | 0.90 | TRPM8 (0.55) | TRPM8MMP8PYGLATMCTRB1 | |
| SCHEMBL5653520 | 0.90 | TRPM8 (0.55) | TRPM8MMP8PYGLATMCTRB1 | |
| SCHEMBL6350990 | 0.87 | TRPM8 (0.61) | TRPM8ATMCTRB1ALDH1A1CTSL | |
| SCHEMBL7414480 | 0.87 | TRPM8 (0.61) | TRPM8ATMCTRB1ALDH1A1CTSL | |
| SCHEMBL7245549 | 0.87 | TRPM8 (0.61) | TRPM8ATMCTRB1ALDH1A1CTSL | |
| SCHEMBL7430937 | 0.87 | TRPM8 (0.61) | TRPM8ATMCTRB1ALDH1A1CTSL | |
| SCHEMBL7418088 | 0.87 | TRPM8 (0.61) | TRPM8ATMCTRB1ALDH1A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307184-B2 | Processes for preparing oxazolidinone derivatives of β-hydroxyethlamine compounds and for preparing β-hydroxyethlamine compounds | KANEKA CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20060135784-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES | KANEKA CORPORATION | 2006-06-22 | — | — | US | disclosed |
| US-7057066-B2 | Process for producing 3-amino-2-hydroxypropionic acid derivatives | KANEKA CORPORATION (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20040181074-A1 | Process for producing oxazolidinone derivative of beta-hydroxyethylamine compound and for producing beta-hydroxyethlamine compound | KANEKA CORPORATION (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1403257-A1 | PROCESSES FOR PRODUCING OXAZOLIDINONE DERIVATIVE OF BETA-HYDROXYETHYLAMINE COMPOUND AND FOR PRODUCING BETA-HYDROXYETHYLAMINE COMPOUND | KANEKA CORPORATION (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-20040049074-A1 | Process for producing 3-amino-2-hydroxypropionic acid derivatives | KANEKA CORPORATION (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1300391-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-5994555-A | (4S,5S)-4-BENZYL-2-OXO-OXAZOLIDINE-5-CARBOXYLIC ACID FROM PHENYLALANINE AND PHTHALIC ANHYDRIDE | F. HOFFMAN-LAROCHE AG (CH) | 1999-11-30 | — | — | US | disclosed |
| US-5859248-A | Process for the production of a β-amino alcohol | F. HOFFMAN-LA ROCHE AG (CH) | 1999-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049074-A1 | Process for producing 3-amino-2-hydroxypropionic acid derivatives | AASDHPPT, HPD, HAAO | TRPM8 4677/4885MMP8 4708/4885PYGL 878/4885 |
| US-20060135784-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES | AASDHPPT, HPD, HAAO | TRPM8 4687/4885MMP8 4700/4885PYGL 863/4885 |
| US-20040181074-A1 | Process for producing oxazolidinone derivative of beta-hydroxyethylamine compound and for producing beta-hydroxyethlamine compound | HNMT, PNMT, HRH4 | TRPM8 3960/4885MMP8 4042/4885PYGL 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.