Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839776 | 0.83 | PTGS2 (0.83) | KMT2APTGS2MAPTALDH1A1POLB | |
| SCHEMBL22307858 | 0.81 | ALDH1A1 (0.58) | KMT2APTGS2MAPTALDH1A1POLB | |
| SCHEMBL11605368 | 0.81 | PTPN7 (0.69) | KMT2APTGS2MAPTALDH1A1POLB | |
| SCHEMBL656776 | 0.80 | PTGS2 (0.66) | KMT2APTGS2MAPTALDH1A1POLB | |
| SCHEMBL832731 | 0.80 | PTGS2 (0.61) | KMT2APTGS2MAPTALDH1A1POLB | |
| SCHEMBL8770416 | 0.79 | ALDH1A1 (0.60) | KMT2AMAPTALDH1A1POLBHPGD | |
| SCHEMBL23605758 | 0.79 | MAPT (0.69) | KMT2AMAPTALDH1A1CYP1A2HPGD | |
| SCHEMBL6602827 | 0.79 | ALDH1A1 (0.62) | KMT2APTGS2MAPTALDH1A1POLB | |
| SCHEMBL22307359 | 0.79 | ALDH1A1 (0.55) | KMT2APTGS2MAPTALDH1A1POLB | |
| SCHEMBL655716 | 0.79 | PTGS2 (0.60) | KMT2APTGS2MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |