Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211298 | 0.83 | IDO1 (0.36) | IDO1PDK2HTTNPSR1MEN1 | |
| SCHEMBL31005154 | 0.83 | IDO1 (0.36) | IDO1PDK2HTTNPSR1MEN1 | |
| SCHEMBL648491 | 0.77 | IDO1 (0.44) | IDO1PDK2HTTNPSR1MEN1 | |
| SCHEMBL31005104 | 0.76 | FFAR1 (0.35) | IDO1PDK2HTTNPSR1MEN1 | |
| SCHEMBL31005157 | 0.76 | FFAR1 (0.35) | IDO1PDK2HTTNPSR1MEN1 | |
| SCHEMBL3201085 | 0.76 | FFAR1 (0.35) | IDO1PDK2HTTNPSR1MEN1 | |
| SCHEMBL3197209 | 0.76 | FFAR1 (0.35) | IDO1PDK2HTTNPSR1MEN1 | |
| SCHEMBL775289 | 0.76 | GABRA1 (0.41) | NPSR1ALDH1A1TSHRMAPT | |
| SCHEMBL11889254 | 0.72 | LIPG (0.33) | ALDH1A1KDM4ETAAR1 | |
| SCHEMBL2722057 | 0.72 | TSHR (0.36) | IDO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795023-A1 | A PROCESS FOR PRODUCING SULPHOXIDE ENRICHED IN THE (R) OR THE (S) ENANTIOMER | ZENECA LIMITED (GB) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996017075-A1 | A PROCESS FOR PRODUCING SULPHOXIDE ENRICHED IN THE (R) OR THE (S) ENANTIOMER | ZENECA LIMITED (GB) | 1996-06-06 | — | — | WO | disclosed |