Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770732 | 0.96 | MAOA (0.47) | MAOAMAOBPTGS2ESR1ESR2 | |
| SCHEMBL8770486 | 0.87 | PTGER1 (0.46) | MAOAMAOBPTGS2PTGS1CYP19A1 | |
| SCHEMBL8770518 | 0.85 | PTGS2 (0.44) | MAOAMAOBPTGS2ESR1ESR2 | |
| SCHEMBL8770553 | 0.84 | PTGER1 (0.53) | MAOAMAOBPTGS2PTGS1KMT2A | |
| SCHEMBL8770492 | 0.83 | PTGER1 (0.58) | MAOAMAOBPTGS2PTGS1KMT2A | |
| SCHEMBL8770509 | 0.81 | PTGER1 (0.58) | MAOAMAOBPTGS2PTGS1KMT2A | |
| SCHEMBL8770407 | 0.80 | PTGER1 (0.49) | MAOAMAOBPTGS2PTGS1PTGER1 | |
| SCHEMBL8770371 | 0.80 | PTGER1 (0.47) | PTGS2PTGS1KMT2APTGER1 | |
| SCHEMBL8770706 | 0.78 | PTGER1 (0.44) | MAOAMAOBPTGS2PTGS1PTGER1 | |
| SCHEMBL8770489 | 0.77 | PTGER1 (0.47) | MAOAMAOBPTGS2PTGS1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566175-B1 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-08-06 | — | — | EP | disclosed |
| US-5371106-A | Reacting arylacetic acid derivative with haloketone derivative in a solvent in presence of stoichiometric amount of base to form phenacyl ester derivative which is cyclized in situ by adding base | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-12-06 | — | — | US | disclosed |
| EP-0566175-A2 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-10-20 | — | — | EP | disclosed |