Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770458 | 0.81 | LTA4H (0.46) | P2RX7GAAMAPTLMNAITGA4 | |
| SCHEMBL1827092 | 0.79 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL7950818 | 0.79 | TDP1 (0.42) | GAAMAPTLMNABCHEACHE | |
| SCHEMBL6154518 | 0.78 | KMT2A (0.40) | P2RX7GAALMNAKMT2AMEN1 | |
| SCHEMBL1827267 | 0.78 | P2RX7 (0.46) | P2RX7GAAMAPTLMNAKMT2A | |
| SCHEMBL5914209 | 0.77 | P2RX7 (0.47) | P2RX7GAAMAPTLMNAITGA4 | |
| SCHEMBL5336287 | 0.77 | P2RX7 (0.47) | P2RX7GAAMAPTLMNAITGA4 | |
| SCHEMBL5914207 | 0.77 | P2RX7 (0.47) | P2RX7GAAMAPTLMNAITGA4 | |
| SCHEMBL27628888 | 0.76 | KCNA5 (0.39) | P2RX7MAPTLMNAKMT2AMEN1 | |
| SCHEMBL6897562 | 0.76 | SLC1A3 (0.51) | MAPTKMT2AMEN1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585397-B1 | BOMBESIN ANALOGS | MERRELL PHARMA INC (US) | 1997-08-06 | — | — | EP | disclosed |