Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421457 | 1.00 | NAAA (0.56) | NAAAHTR2CNPSR1RAD52FAAH | |
| SCHEMBL5721004 | 0.95 | NAAA (0.48) | NAAAHTR2CNPSR1RAD52FAAH | |
| SCHEMBL30998049 | 0.93 | NAAA (0.47) | NAAAHTR2CNPSR1RAD52DGKA | |
| SCHEMBL5720929 | 0.91 | NAAA (0.44) | NAAAHTR2CNPSR1DGKAMAPT | |
| SCHEMBL4935831 | 0.88 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL4931761 | 0.88 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL3223213 | 0.86 | TP53 (0.44) | S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL1140577 | 0.86 | TP53 (0.44) | S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL31528814 | 0.85 | DGKA (0.65) | NAAAHTR2CDGKAMAPTPRSS1 | |
| SCHEMBL31528807 | 0.85 | DGKA (0.65) | NAAAHTR2CDGKAMAPTPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018633-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1996-06-20 | — | — | WO | disclosed |