Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223213 | 1.00 | TP53 (0.44) | TP53OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL4935831 | 0.98 | S1PR2 (0.46) | TP53OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL28682838 | 0.98 | S1PR2 (0.46) | TP53OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL4931761 | 0.98 | S1PR2 (0.46) | TP53OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL4934729 | 0.94 | CYP1A2 (0.42) | TP53S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL5720929 | 0.87 | NAAA (0.44) | TP53S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL5721004 | 0.87 | NAAA (0.48) | S1PR2S1PR1S1PR3S1PR4ALDH1A1 | |
| SCHEMBL28410817 | 0.87 | CYP1A2 (0.53) | CYP1A2ALDH1A1MGAMGAASI | |
| SCHEMBL10602600 | 0.86 | MGAM (0.44) | CYP1A2ALDH1A1MGAMGAASI | |
| SCHEMBL1294363 | 0.86 | MGAM (0.44) | CYP1A2ALDH1A1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015189862-A1 | CHIRAL AMINES, A PROCESS FOR PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-17 | — | — | WO | claimed |
| WO-2015189862-A1 | CHIRAL AMINES, A PROCESS FOR PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-17 | — | — | WO | disclosed |
| US-8383547-B2 | Aflatoxin production inhibitor and method for controlling aflatoxin contamination using the same | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2013-02-26 | — | — | US | disclosed |
| US-20120190746-A1 | AFLATOXIN PRODUCTION INHIBITOR AND METHOD FOR CONTROLLING AFLATOXIN CONTAMINATION USING THE SAME | THE UNIVERSITY OF TOKYO (JP) | 2012-07-26 | — | — | US | disclosed |
| US-7915019-B2 | Processes for preparing optically active (S or R)-β-amino acid and optically active (R or S)-β-amino acid ester, and β-amino acid 2-alkoxyethyl ester and optically active (S or R)-β amino acid 2-alkoxyethyl ester | UBE INDUSTRIES, LTD. (JP) | 2011-03-29 | — | — | US | disclosed |
| EP-1840218-B1 | Process for production of optically active (S)- or (R)-beta-amino acids and optically active (R)- or (S)-beta -amino acid esters, and optically active (S)- or (R)-2-alkoxyethyl esters of beta-amino acids. | UBE INDUSTRIES (JP) | 2011-02-23 | — | — | EP | disclosed |
| US-20100063150-A1 | Aflatoxin Production Inhibitor and Method for Controlling Aflatoxin Contamination Using the Same | THE UNIVERSITY OF TOKYO (JP) | 2010-03-11 | — | — | US | disclosed |
| US-20090117626-A1 | Process for preparing carboxylic acid using surfactant-modified enzyme | UBE INDUSTRIES, LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20080312080-A1 | Novel dioctatin derivatives and production process thereof | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2008-12-18 | — | — | US | disclosed |
| US-20080038785-A1 | Processes For Preparing Optically Active (S Or R-)-Beta-Amino Acid And Optically Active (R Or S)-Beta-Amino Acid Ester, And Beta-Amino Acid 2-Alkoxyethyl Ester And Optically Active (S Or R)-Beta Amino Acid 2-Alkoxyethyl Ester | UBE INDUSTRIES, LTD. (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1887086-A1 | PROCESS FOR PRODUCTION OF CARBOXYLIC ACID USING SURFACTANT-MODIFYING ENZYME | Ube Industries, Ltd. (JP) | 2008-02-13 | — | — | EP | disclosed |
| EP-1840218-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE (S)- OR (R)- BETA-AMINO ACIDS AND OPTICALLY ACTIVE (R)- OR (S)-BETA -AMINO ACID ESTERS, 2-ALKOXYETHYL ESTERS OF -AMINO ACIDS, AND OPTICALLY ACITVE (S)- OR (R)-2-ALKOXYETHYL ESTERS OF -AMINO ACIDS | Ube Industries, Ltd. (JP) | 2007-10-03 | — | — | EP | disclosed |
| US-20060178433-A1 | 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto | UBE INDUSTRIES, LTD. (JP) | 2006-08-10 | — | — | US | disclosed |
| EP-1621529-A1 | 3-AMINO-3-ARYLPROPIONIC ACID n-ALKYL ESTERS, PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-3-ARYLPROPIONIC ACIDS AND ESTERS OF THE ANTIPODES THERETO | Ube Industries, Ltd. (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-0918059-B1 | Substituted imidazoline derivatives, their preparation, their use, and pharmaceutical compositions containing them | AVENTIS PHARMA GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| EP-0918059-A1 | Substituted imidazoline derivatives, their preparation, their use, and pharmaceutical compositions containing them | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190746-A1 | AFLATOXIN PRODUCTION INHIBITOR AND METHOD FOR CONTROLLING AFLATOXIN CONTAMINATION USING THE SAME | AKR7A2, CYP51A1, DIMT1 | TP53 897/4885OPRM1 4875/4885S1PR2 4704/4885 |
| US-20060178433-A1 | 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto | ALAD, ARSA, ALDH7A1 | TP53 4725/4885OPRM1 1954/4885S1PR2 2543/4885 |
| US-20080312080-A1 | Novel dioctatin derivatives and production process thereof | AKR7A2, HDHD5, DECR1 | TP53 2346/4885OPRM1 4872/4885S1PR2 4302/4885 |
| US-20100063150-A1 | Aflatoxin Production Inhibitor and Method for Controlling Aflatoxin Contamination Using the Same | AKR7A2, DIMT1, CYP51A1 | TP53 1435/4885OPRM1 4861/4885S1PR2 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.