Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541703 | 0.89 | SIGMAR1 (0.44) | SIGMAR1TAAR1 | |
| SCHEMBL5541551 | 0.87 | SIGMAR1 (0.41) | SIGMAR1TAAR1 | |
| SCHEMBL5536973 | 0.81 | CA12 (0.41) | SIGMAR1TAAR1MAPT | |
| SCHEMBL14149523 | 0.80 | MAPT (0.53) | LSSAPPTAAR1PTGESALOX5 | |
| SCHEMBL17037834 | 0.79 | SIGMAR1 (0.52) | SIGMAR1TAAR1 | |
| SCHEMBL13645984 | 0.77 | SIGMAR1 (0.48) | SIGMAR1TAAR1 | |
| SCHEMBL73319 | 0.73 | CA12 (0.44) | SIGMAR1TAAR1HTR2A | |
| SCHEMBL11145951 | 0.72 | CA12 (0.47) | SIGMAR1TAAR1MAPT | |
| SCHEMBL8770783 | 0.72 | MTNR1A (0.45) | — | |
| SCHEMBL23504507 | 0.72 | SIGMAR1 (0.46) | SIGMAR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018633-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1996-06-20 | — | — | WO | disclosed |