Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541703 | 0.81 | SIGMAR1 (0.44) | HTR7 | |
| SCHEMBL5541551 | 0.79 | SIGMAR1 (0.41) | HTR7 | |
| SCHEMBL5535156 | 0.79 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL5526550 | 0.75 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1HTR7FDFT1 | |
| SCHEMBL5535639 | 0.74 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL5536973 | 0.74 | CA12 (0.41) | HTR7 | |
| SCHEMBL9786534 | 0.73 | LTA4H (0.55) | MTNR1AMTNR1BKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5669695 | 0.72 | BCHE (0.53) | KDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL8770809 | 0.72 | LSS (0.40) | — | |
| SCHEMBL5536841 | 0.72 | MTNR1A (0.58) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018633-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1996-06-20 | — | — | WO | disclosed |