Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612468 | 0.84 | CYP19A1 (0.52) | CYP19A1CYP11B2TDP1ESR1PTGS2 | |
| SCHEMBL133220 | 0.81 | MAPT (0.39) | TDP1MAPTGAAALOX15CYP3A4 | |
| SCHEMBL28880691 | 0.78 | ESR1 (0.61) | CYP19A1CYP11B2TDP1ESR1MAPT | |
| SCHEMBL561349 | 0.77 | CYP19A1 (0.47) | CYP19A1CYP11B2TDP1ESR1MAPT | |
| SCHEMBL10606922 | 0.75 | TSHR (0.38) | TDP1MAPTGAAHDAC3MAPK1 | |
| SCHEMBL10606918 | 0.75 | TSHR (0.38) | TDP1MAPTGAAHDAC3MAPK1 | |
| SCHEMBL15089108 | 0.75 | ALOX15 (0.43) | TDP1MAPTGAAALOX15CYP3A4 | |
| SCHEMBL6481707 | 0.74 | TDP1 (0.56) | CYP19A1CYP11B2TDP1ESR1GAA | |
| SCHEMBL987337 | 0.74 | HSD11B1 (0.44) | CYP19A1CYP11B2TDP1ESR1MAPT | |
| SCHEMBL9806295 | 0.74 | ALDH1A1 (0.46) | CYP19A1CYP11B2TDP1ESR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1665357-A | Method of producing laminated type organic electroluminescent element and display apparatus | SEIKO EPSON CORP (JP) | 2005-09-07 | — | — | CN | disclosed |
| EP-0560311-B1 | Electrophotographic photoreceptor | KONISHIROKU PHOTO IND (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5350655-A | Conductive substrates with photosensitive layers of diols and binders | KONICA CORPORATION (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0560311-A1 | Electrophotographic photoreceptor | KONICA CORPORATION (JP) | 1993-09-15 | — | — | EP | disclosed |