Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | EEF2K | O00418 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771339 | 0.85 | CES2 (0.51) | CES2CES1EEF2KMEN1KMT2A | |
| SCHEMBL5685248 | 0.84 | EEF2K (0.50) | CES2CES1EEF2KMEN1KMT2A | |
| SCHEMBL11495829 | 0.81 | CES2 (0.46) | CES2CES1EEF2KMEN1KMT2A | |
| SCHEMBL2457680 | 0.79 | EEF2K (0.47) | CES2CES1EEF2KMEN1KMT2A | |
| SCHEMBL7236109 | 0.79 | EEF2K (0.47) | CES2CES1EEF2KMEN1KMT2A | |
| SCHEMBL3511352 | 0.79 | EEF2K (0.47) | CES2CES1EEF2KMEN1KMT2A | |
| SCHEMBL6443530 | 0.79 | EEF2K (0.50) | CES2CES1EEF2KMEN1KMT2A | |
| SCHEMBL28032089 | 0.79 | MEN1 (0.44) | CES2CES1MEN1KMT2ACNR2 | |
| SCHEMBL8770892 | 0.79 | MEN1 (0.44) | CES2CES1MEN1KMT2ACNR2 | |
| SCHEMBL30556756 | 0.78 | AKR1B1 (0.45) | CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |