Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 4/20 | 0.45 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770868 | 0.84 | CES2 (0.49) | EEF2KMEN1KMT2ACNR2CES2 | |
| SCHEMBL7236109 | 0.82 | EEF2K (0.47) | EEF2KMEN1KMT2ACNR2CES2 | |
| SCHEMBL3511352 | 0.82 | EEF2K (0.47) | EEF2KMEN1KMT2ACNR2CES2 | |
| SCHEMBL2457680 | 0.82 | EEF2K (0.47) | EEF2KMEN1KMT2ACNR2CES2 | |
| SCHEMBL6443530 | 0.82 | EEF2K (0.50) | EEF2KMEN1KMT2ACNR2CES2 | |
| SCHEMBL18683363 | 0.81 | EEF2K (0.46) | EEF2KMEN1KMT2ACNR2CES2 | |
| SCHEMBL31084151 | 0.80 | CNR2 (0.46) | EEF2KMEN1KMT2ACNR2CES2 | |
| SCHEMBL5685100 | 0.80 | CNR2 (0.50) | EEF2KMEN1KMT2ACNR2CES2 | |
| SCHEMBL6261167 | 0.80 | CNR2 (0.43) | EEF2KMEN1KMT2ACNR2CES2 | |
| SCHEMBL3826164 | 0.78 | EEF2K (0.44) | EEF2KMEN1KMT2ACNR2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640359-A2 | ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES | NPS PHARMACEUTICALS, INC. (US) | 2006-03-29 | — | — | EP | disclosed |
| EP-1042275-B1 | ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES | NPS PHARMA INC (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20030199589-A1 | Anticonvulsant and central nervous system-depressing bis (fluorophenyl) alkylamides and their uses | NPS PHARMACEUTICALS, INC. | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199589-A1 | Anticonvulsant and central nervous system-depressing bis (fluorophenyl) alkylamides and their uses | GABRE, GABRA2, GABRB2 | EEF2K 1612/4885MEN1 3260/4885KMT2A 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.