Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771128 | 0.89 | ADRA1A (0.60) | ADRA1AADRA2AALOX15LMNACYP1A2 | |
| SCHEMBL8770929 | 0.87 | ADRA1A (0.49) | ADRA1AADRA2ALMNACYP1A2TSHR | |
| SCHEMBL312971 | 0.82 | POLB (0.48) | LMNACYP1A2TSHR | |
| SCHEMBL8770899 | 0.82 | ADRA1A (0.50) | ADRA1AADRA2ALMNACYP1A2TSHR | |
| SCHEMBL8770941 | 0.82 | ADRA1A (0.44) | ADRA1AADRA2ALMNACYP1A2TSHR | |
| SCHEMBL14188940 | 0.81 | MAPT (0.50) | LMNACYP2C19 | |
| SCHEMBL1044605 | 0.80 | ALDH1A1 (0.45) | ADRA1AADRA2AALOX15LMNATSHR | |
| SCHEMBL9173075 | 0.79 | ADRA2A (0.56) | ADRA1AADRA2A | |
| SCHEMBL491096 | 0.78 | HIF1A (0.46) | TSHR | |
| SCHEMBL28929914 | 0.78 | PPARG (0.53) | LMNACYP1A2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |