Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685475 | 0.87 | MAPT (0.55) | MAPTPOLBMAPK1LMNAHDAC4 | |
| SCHEMBL12836547 | 0.85 | MAPT (0.45) | MAPTPOLBMAPK1CES2CES1 | |
| SCHEMBL987559 | 0.85 | MAPT (0.45) | MAPTPOLBMAPK1CES2CES1 | |
| SCHEMBL8770903 | 0.85 | L3MBTL1 (0.49) | MAPTPOLBMAPK1CES2CES1 | |
| SCHEMBL8770949 | 0.84 | CES2 (0.40) | MAPTCES2CES1LMNAMEN1 | |
| SCHEMBL5720988 | 0.84 | MAPT (0.44) | MAPTPOLBMAPK1LMNAHDAC4 | |
| SCHEMBL7403590 | 0.84 | MAPT (0.44) | MAPTPOLBMAPK1LMNAHDAC4 | |
| Hydrochloric Acid SCHEMBL7339173 | 0.83 | MAPT (0.43) | MAPTPOLBMAPK1LMNAHDAC4 | |
| Hydrochloric Acid SCHEMBL7902491 | 0.83 | MAPT (0.43) | MAPTPOLBMAPK1LMNAHDAC4 | |
| SCHEMBL8770972 | 0.82 | L3MBTL1 (0.43) | MAPTL3MBTL1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |