Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605867 | 1.00 | L3MBTL1 (0.43) | L3MBTL1CTSANPSR1ADORA3ALDH1A1 | |
| SCHEMBL30152920 | 0.85 | KCNA5 (0.43) | L3MBTL1CTSANPSR1ADORA3ALDH1A1 | |
| SCHEMBL29190132 | 0.85 | KCNA5 (0.43) | L3MBTL1CTSANPSR1ADORA3ALDH1A1 | |
| SCHEMBL8770921 | 0.85 | KCNA5 (0.50) | L3MBTL1 | |
| SCHEMBL8771047 | 0.84 | GPR35 (0.39) | NPSR1ALDH1A1MAPT | |
| SCHEMBL20545317 | 0.84 | F10 (0.42) | L3MBTL1CTSANPSR1ADORA3ALDH1A1 | |
| SCHEMBL22699240 | 0.84 | F10 (0.42) | L3MBTL1CTSANPSR1ADORA3ALDH1A1 | |
| SCHEMBL21476155 | 0.84 | F10 (0.42) | L3MBTL1CTSANPSR1ADORA3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19067189 | 0.83 | IDO1 (0.43) | CTSANPSR1ADORA3ALDH1A1MAPT | |
| SCHEMBL8770943 | 0.82 | MAPT (0.45) | L3MBTL1MAPTF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288429-A1 | LACTAMS AS CBL-B INHIBITORS | Genentech, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-116888112-A | Lactams as CBL-B inhibitors | 基因泰克公司 | 2023-10-13 | — | — | CN | disclosed |
| WO-2022169997-A1 | LACTAMS AS CBL-B INHIBITORS | GENENTECH, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |