Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 2/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CPA3 | P15088 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771210 | 0.85 | SLC18A3 (0.46) | CYP26A1HTTCYP2C9HPGDCYP2C19 | |
| SCHEMBL8771032 | 0.81 | CYP2C9 (0.45) | HTTCYP2C9CYP2C19TSHR | |
| SCHEMBL11784289 | 0.81 | FFAR1 (0.41) | CYP26A1HTTCYP2C9HPGDCYP2C19 | |
| SCHEMBL8770898 | 0.78 | NLRP3 (0.41) | CYP2C9CYP2C19TSHR | |
| SCHEMBL7143938 | 0.77 | TAAR1 (0.38) | HPGDTSHR | |
| SCHEMBL8770959 | 0.77 | KMT2A (0.37) | HTTCYP2C9CYP2C19 | |
| SCHEMBL29249378 | 0.74 | CYP1A2 (0.39) | HTTCYP2C9HPGDCYP2C19CYP1A2 | |
| SCHEMBL30437060 | 0.72 | GABBR2 (0.48) | CYP26A1HTTCYP2C9HPGDCYP2C19 | |
| SCHEMBL658742 | 0.72 | GABBR2 (0.48) | CYP26A1HTTCYP2C9HPGDCYP2C19 | |
| SCHEMBL30556756 | 0.72 | AKR1B1 (0.45) | HTTHPGDCYP1A2TSHRCPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |