SCHEMBL29249378

SCHEMBL29249378

O=C(O)CC(O)c1ccccc1I

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.39
TSHR P16473 2/20 0.39
CPA1 P15085 2/20 0.39
GABBR2 O75899 1/20 0.39
GABBR1 Q9UBS5 1/20 0.39
CPB1 P15086 1/20 0.39
CPA3 P15088 1/20 0.39
CPB2 Q96IY4 1/20 0.39
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP12 P39900 1/20 0.38
MMP13 P45452 1/20 0.38
MMP14 P50281 1/20 0.38
CYP2C19 P33261 3/20 0.37
CYP2C9 P11712 2/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5720972 0.79 GABBR2 (0.42) CYP1A2TSHRCPA1GABBR2GABBR1
SCHEMBL5720977 0.79 GABBR2 (0.42) CYP1A2TSHRCPA1GABBR2GABBR1
SCHEMBL30556756 0.78 AKR1B1 (0.45) CYP1A2TSHRCPA1GABBR2GABBR1
SCHEMBL9579846 0.78 AKR1B1 (0.45) CYP1A2TSHRCPA1GABBR2GABBR1
SCHEMBL8771210 0.77 SLC18A3 (0.46) CYP1A2TSHRCPA1GABBR2GABBR1
SCHEMBL8770868 0.77 CES2 (0.49) CYP1A2TSHR
SCHEMBL3448381 0.77 CTSA (0.47)
SCHEMBL8771196 0.77 ADRB2 (0.50) CYP2D6
SCHEMBL11397704 0.76 KMT2A (0.44) CYP1A2TSHRCPA1GABBR2GABBR1
SCHEMBL11050837 0.75 CYP2D6 (0.36) TSHRKDM4ECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324724-A Multifunctional diagnosis and treatment nano material and preparation method and application thereof 东南大学 2024-07-12 CN claimed
CN-118324724-A Multifunctional diagnosis and treatment nano material and preparation method and application thereof 东南大学 2024-07-12 CN disclosed