Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149908 | 0.85 | HDAC4 (0.51) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL3443316 | 0.84 | L3MBTL1 (0.60) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL5857867 | 0.84 | GABBR2 (0.50) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL7426107 | 0.81 | CES2 (0.47) | CES2CES1FFAR1CTSAEEF2K | |
| SCHEMBL3511663 | 0.81 | KMT2A (0.55) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL5720869 | 0.81 | KMT2A (0.55) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL4011437 | 0.81 | KMT2A (0.55) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL22303914 | 0.81 | FFAR1 (0.49) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL12883017 | 0.81 | FFAR1 (0.49) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL30661805 | 0.81 | KMT2A (0.55) | CES2CES1HDAC4HDAC7HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |